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US 2017/0335287 A1Published application
Methods and compositions to maintain stem cell quiescence
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsMarco Quarta, Thomas A. Rando
Life of this patent
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Abstract
Compositions and methods are provided for induction and maintenance of quiescence of stem cells.
Claims14
A medium that provides quiescence of stem cells during in vitro culture comprising one or more of components:
- Elcatonin, SB203580, SU5402, Forskolin, TGFbeta, Knock Out SR, and insulin-transferrin-selenium (ITS, Invitrogen).
A medium that provides quiescence of stem cells during in vitro culture comprising one or more of components:
- elcatonin;
- MGCD-265, JNJ-7706621, Forskolin, Somatostatin, SB203580, SU5402, TGFbeta and serum replacement.
An isolated population of quiescent stem cells generating by the method of claim
Dependencies are inferred from the claim text.