Treatment of diseases asssociated with fat accumulation
AssigneeThe Provost, Fellows, Foundation Scholars, and the other Members of Board, of the College of the
InventorsPadraic FALLON, Emily HAMS
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Abstract
The present invention is directed to immunmodulators in the form of compositions, compounds, proteins and/or fragments with RNase activity thereof for use in the treatment of diseases associated with fat accumulation, including obesity and obesity-related disorders and metabolic disorders.
Claims21
1-19. (canceled)
A method for the treatment of diseases associated with fat accumulation, comprising the administration of a ribonuclease protein of the T2 family, or a fragment thereof that induces IL-33 release to initiate a type 2, optionally in adipose cells and/or tissues, to a subject in need thereof.
A pharmaceutical composition comprising a ribonuclease protein of the T2 family, or a fragment thereof that induces IL-33 release to initiate a type 2, preferably in adipose cells and/or tissues.
Dependencies are inferred from the claim text.