Radiopharmaceutical production system, radiopharmaceutical production device, and production method for radiopharmaceuticals
AssigneeHitachi, Ltd.
InventorsYuuko KANI, Takahiro TADOKORO
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Abstract
The present invention comprises: an electron beam accelerator (2); a container (4) housing a raw material (3) for radioactive nuclide production, said raw material including molybdenum 100; a heating device (5) that heats the raw material (3) for radioactive nuclide production; an adsorbent (81) that adsorbs technetium compounds including technetium 99m generated by the heated raw material (3) for radioactive nuclide production; an eluent supply device (10) that supplies an eluent (L1) that causes elution of the technetium compound adsorbed to the adsorbent (81); and a drug recovery unit (13) that recovers the eluent (L2).
Claims15
A radiopharmaceutical production system comprising:
- a radionuclide production device that produces molybdenum 99 by nuclear reaction through irradiation of a molybdenum 100-containing radionuclide feedstock with radiation generated by using electrons accelerated with an electron beam accelerator;
- and
- a radiopharmaceutical production device that heats the radionuclide feedstock to evaporate a technetium compound containing technetium 99m generated by radioactive decay of molybdenum 99, and adsorbs the evaporated technetium 99m-containing technetium compound to an adsorbent, and in which an eluent is passed through the adsorbent adsorbing the technetium 99m-containing technetium compound, and the technetium 99m-containing technetium compound is eluted into the eluent to produce a radiopharmaceutical.
A radiopharmaceutical production device comprising:
- an electron beam accelerator;
- a container for housing a molybdenum 100-containing radionuclide feedstock to be irradiated with radiation generated by using electrons accelerated with the electron beam accelerator;
- a heater for heating the radionuclide feedstock housed in the container;
- an adsorbent that adsorbs a technetium compound, the technetium compound contains technetium 99m, the technetium compound is generated upon heating the radionuclide feedstock irradiated with the radiation;
- an eluent feeder that supplies an eluent for eluting from the adsorbent the technetium 99m-containing technetium compound adsorbed to the adsorbent;
- and
- a drug collecting section that collects the eluent.
A method for producing a radiopharmaceutical,
- the method comprising:
- producing molybdenum 99 by nuclear reaction through irradiation of a molybdenum 100-containing radionuclide feedstock with radiation generated by using electrons accelerated with an electron beam accelerator;
- heating the radionuclide feedstock to evaporate a technetium compound containing technetium 99m produced by radioactive decay of molybdenum 99;
- adsorbing the evaporated technetium 99m-containing technetium compound to an adsorbent;
- and
- passing an eluent through the adsorbent adsorbing the technetium 99m-containing technetium compound, and eluting the technetium 99m-containing technetium compound into the eluent to produce a radiopharmaceutical.
Dependencies are inferred from the claim text.