Prediction marker
AssigneeTohoku University
InventorsNoriko OSUMI, Kaichi YOSHIZAKI
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Abstract
An object of the present invention is to provide a prediction marker in male animals for predicting behaviors of their offspring. Specifically, isolated H3K79me3 from a spermatocyte or a sperm of a male animal is used as a marker. When levels of methylation of H3K79me3 in a spermatocyte or a sperm which has been collected from male animals are analyzed, those with a lower level of trimethylation of H3K79me3 have a higher probability of their offspring having autism or exhibiting autism-like behaviors.
Claims7
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A method of predicting a behavior of an offspring of a male animal, the method comprising the step of:
- determining a level of methylation of a H3K79me3 in a spermatocyte or a sperm collected from the male animal.
Dependencies are inferred from the claim text.