Sensing method

Abstract

To provide a technique for performing a highly reliable measurement in sensing a sensing object in a sample solution based on a frequency variation of the crystal resonator 4. In a sensing method that causes the sensing object to attach to the crystal resonator 4 and measures an amount of the sensing object from the frequency variation caused by an effect of mass addition, an oscillation frequency is measured before a measurement region is caused to be in a liquid phase, and subsequently the sample solution is supplied to the measurement region. Thereafter, a liquid component in the measurement region is removed to cause the measurement region to be in a gas phase. An oscillation frequency is measured to measure a frequency difference from the oscillation frequency before the sample solution is supplied to the measurement region. Therefore, since a piezoelectric resonator oscillates in the gas phase, an error of the oscillation frequency and a decrease in a variation amount of the oscillation frequency caused by the crystal resonator 4 contacting a liquid phase are restrained, thus ensuring sensing the sensing object with high accuracy.

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