US 2017/0320956 A1Published application

Anti-light antibodies

AssigneeKymab Limited

InventorsJamie Iain CAMPBELL, Bettina FRANZ, Steve HOLMES, Ian KIRBY, Anais LEGENT

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Abstract

The present invention relates to anti-human LIGHT antibodies, new medical uses and methods.

Claims34

Dependent claims

An antibody or a fragment thereof, that specifically binds to human lymphotoxin-like, exhibits inducible expression and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes 214E allele (214E hLIGHT) and competes for binding to said 214E hLIGHT with an antibody selected from the group consisting of 1C02, 13H04 and 31A10.

Dependencies are inferred from the claim text.

Facts

Application: 15/624,765Filed 16 Jun 2017
Priority: GB 1400597.914 Jan 2014
Published: 9 Nov 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification26 codes

C07K 16/2875
Against receptors, cell surface antigens or cell surface determinants: against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
A61K 39/00
Medicinal preparations containing antigens or antibodies
A61K 39/0008
Vertebrate antigens: antigens related to auto-immune diseases; Preparations to induce self-tolerance
A61P 1/02
Drugs for disorders of the alimentary tract or the digestive system: stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Family

Application15/110,487Continuation · filed 8 Jul 2016
Application15/624,765Continuation
US 10,259,880 B2Related patent
US 2017/0291951 A1Published application
US 2017/0320956 A1This patent

From the US filing history. Foreign family members aren’t listed.

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