Antibodies against human csf-1r and uses thereof
AssigneeHoffmann-La Roche Inc.
InventorsNikolaos DIMOUDIS, Georg FERTIG, Alexander FIDLER, Klaus KALUZA, Marlene THOMAS, Carola RIES, Stefan SEEBER, Martin LANZENDOERFER (DECEASED)
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Abstract
The present invention relates to antibodies against human CSF-1R (anti-CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
Claims20
An isolated antibody binding to human CSF-1R, wherein the antibody comprises a heavy chain variable domain and a light chain variable domain, and wherein the heavy chain variable domain comprises a CDR3 region comprising SEQ ID NO:
- 77, a CDR2 region comprising SEQ ID NO:
- 78, and a CDR1 region comprising SEQ ID NO:
- 79, and the light chain variable domain comprises a CDR3 region comprising SEQ ID NO:
- 80, a CDR2 region comprising SEQ ID NO:
- 81, and a CDR1 region comprising SEQ ID NO:
- 82.
An isolated antibody binding to human CSF-1R, wherein the antibody comprises a heavy chain variable domain and a light chain variable domain, and wherein the heavy chain variable domain comprises SEQ ID NO:
- 83 and the light chain variable domain comprises SEQ ID NO:
- 84.
Dependencies are inferred from the claim text.