Novel 4-(aryl)-n-(2-alkoxythieno[3,2-b]pyrazin-3-yl)-piperazine-1-carboxamide derivative, and antiproliferative effect thereof
AssigneeDongguk University Industry-Academic Cooperation Foundation
InventorsYoung Dae Gong, Se Hun Kwak, Eun Sil Lee
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Abstract
The present invention relates to a novel 4-(aryl)-N-(2-alkoxythieno[3,2-b]pyrazin-3 -y)-piperazin-1-carboxamide derivative compound useful in the prevention or treatment of cancer; a preparation method thereof; and a pharmaceutical composition comprising the same. The novel 4-(aryl)-N(2-alkoxythieno[3,2-b]pyrazin-3-yl)-piperazin-1-carboxamide derivative compound of the present invention can effectively inhibit the growth of proliferating cells, and thus can be useful in the prevention or treatment of cancer.
Claims19
A compound represented by the following Formula 1 or a pharmaceutically acceptable salt thereof:
- wherein, in the above formula,
- R1 is hydrogen or halogen;
- R2 is linear or branched C1-6 alkyl;
- and
- R3 to R7 are each independently hydrogen, halogen, linear or branched C1-6 alkyl, linear or branched C1-6 haloalkyl, C1-6 alkoxy, or C1-6 haloalkoxy.
Dependencies are inferred from the claim text.