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AssigneeNippon Menard Cosmetic Co., Ltd.
InventorsSeiji HASEGAWA, Yu INOUE, Yuichi HASEBE, Tsutomu SAKAIDA
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An object of the present invention is to find a novel substance that is capable of efficiently promoting the proliferation of stem cells while maintaining the undifferentiated state thereof and to provide the substance as an agent for maintaining the undifferentiated state of stem cells or an agent for promoting the proliferation of stem cells. Another object of the present invention is to provide an agent for treating a wound that has a wound healing effect on the skin and is readily available in the field of skin regenerative medicine or cosmetic treatment, and safe and inexpensive. The present invention relates to an agent for maintaining the undifferentiated state or promoting the proliferation of stem cells or an agent for treating a wound, comprising, as an active ingredient, one or a mixture of two or more of fatty acid glycerides represented by the following general formula (I): wherein at least one of R1, R2, and R3 represents an acyl group derived from an unsaturated fatty acid having 16 to 22 carbon atoms and the others each represent an acyl group derived from a saturated fatty acid or a hydrogen atom.
An agent for maintaining the undifferentiated state of stem cells, comprising, as an active ingredient, one or a mixture of two or more of fatty acid glycerides represented by the following general formula (I):
An agent for promoting the proliferation of stem cells, comprising, as an active ingredient, one or a mixture of two or more of fatty acid glycerides represented by the following general formula (I):
An agent for treating a wound, comprising, as an active ingredient, one or a mixture of two or more of fatty acid glycerides represented by the following general formula (I):
A method for producing stem cells, comprising culturing stem cells in a medium comprising one or a mixture of two or more of fatty acid glycerides represented by the following general formula (I):
A method for maintaining the undifferentiated state of stem cells, comprising culturing stem cells in a medium comprising one or a mixture of two or more of fatty acid glycerides represented by the following general formula (I):
A method for promoting the proliferation of stem cells, comprising culturing stem cells in a medium comprising one or a mixture of two or more of fatty acid glycerides represented by the following general formula (I):
Dependencies are inferred from the claim text.