Systems and methods for performing online extracorporeal photopheresis
AssigneeFenwal, Inc.
InventorsKyungyoon Min, Katherine Radwanski
Life of this patent
Estimating the term…
Abstract
Systems and methods for performing online extracorporeal photopheresis of mononuclear cells are disclosed. Whole blood is removed from a patient and introduced through a processing set into a separation chamber to separate the desired cell population from the blood. The separated cell population is processed through the set which is associated with a treatment chamber where the cells are treated. Once treated, the cells are returned to the patient. The processing set remains connected to the patient during the entire ECP treatment procedure and provides an online, sterile closed pathway between the separation chamber and the treatment chamber.
Claims7
-17. (canceled)
A method for treating a cellular product in a cell therapy comprising:
- a) collecting a desired cellular product from a source of a biological fluid including desired cells in a unitary disposable fluid circuit;
- b) combining said cellular product with saline or plasma in an amount effective to arrive at a desired dilution of the collected cell product for said treatment within said fluid circuit;
- c) combining said cellular product with a photoactivation agent in an amount effective for said cell treatment within said fluid circuit;
- d) treating said cellular product to arrive at a treated product;
- e) introducing said treated product into a separation chamber of a separator;
- f) separating said treated product within said fluid circuit to arrive at a treated cell fraction and a supernatant fraction;
- and
- g) directing said treated cell fraction through said fluid circuit to a patient.
Dependencies are inferred from the claim text.