Blood treatment systems and methods

A hemodialysis system that includes a dialysate mixing circuit, the system comprising:

• a first port fluidly connected to a first pump in the dialysate mixing circuit, the first port configured to connect to a bicarbonate charge line, the bicarbonate charge line arranged to convey fluid from the first pump to an inlet of a bicarbonate source;
• a second port fluidly connected to a second pump in the dialysate mixing circuit, the second port configured to connect to a bicarbonate return line, the bicarbonate return line arranged to convey a bicarbonate solution from an outlet of the bicarbonate source to the second pump;
• a third port fluidly connected to a third pump in the dialysate mixing circuit, the third port configured to connect to an acid flow line, the acid flow line arranged to convey an acid solution from an acid source to the third pump;
• and
• a controller of the hemodialysis system configured to cause the application of negative pressure on the bicarbonate charge line, the bicarbonate return line, or the acid flow line to confirm the ports are not open to atmosphere.

A hemodialysis system that includes a dialysate mixing circuit, the system comprising:

• a first port fluidly connected to a first pump in the dialysate mixing circuit, the first port configured to connect to a bicarbonate charge line, the bicarbonate charge line arranged to convey fluid from the first pump to an inlet of a bicarbonate source;
• a second port fluidly connected to a second pump in the dialysate mixing circuit, the second port configured to connect to a bicarbonate return line, the bicarbonate return line arranged to convey a bicarbonate solution from an outlet of the bicarbonate source to the second pump;
• a third port fluidly connected to a third pump in the dialysate mixing circuit, the third port connected to an acid flow line, the acid flow line arranged to convey an acid solution from an acid source to the third pump;
• wherein the ports are enclosable by one or more doors, so that the one or more doors must be open for tubing to be connected between the bicarbonate source or the acid source and the dialysate mixing circuit of the hemodialysis system.

A hemodialysis system that includes a dialysate mixing circuit, the system including connection ports comprising:

• a first port fluidly connected to a first pump in the dialysate mixing circuit, the first port configured to connect to a bicarbonate charge line, the bicarbonate charge line arranged to convey fluid from the first pump to an inlet of a bicarbonate source;
• a second port fluidly connected to a second pump in the dialysate mixing circuit, the second port configured to connect to a bicarbonate return line, the bicarbonate return line arranged to convey a bicarbonate solution from an outlet of the bicarbonate source to the second pump;
• a third port fluidly connected to a third pump in the dialysate mixing circuit, the third port configured to connect to an acid flow line, the acid flow line arranged to convey an acid solution from an acid source to the third pump;
• and
• a bypass connector comprising three fluid prongs configured to connect with the first, the second, and the third ports, wherein channels in each of the three fluid prongs of the bypass connector terminate within a common chamber within the bypass connector, so that the bicarbonate charge line, the bicarbonate return line and the acid flow line are fluidly connected to each other upon connection of the bypass connector to the first, the second, and the third ports.

In a hemodialysis system, an assembly for interconnecting fluid lines that are configured to connect to an inlet and an outlet of a bicarbonate source and a fluid line configured to connect to an acid source, the assembly comprising:

• a first port fluidly connected to a first pump in a dialysate mixing circuit of the hemodialysis system, the first port configured to connect to a bicarbonate charge line, the bicarbonate charge line arranged to convey fluid from the first pump to an inlet of a bicarbonate source;
• a second port fluidly connected to a second pump in the dialysate mixing circuit, the second port configured to connect to a bicarbonate return line, the bicarbonate return line arranged to convey a bicarbonate solution from an outlet of the bicarbonate source to the second pump;
• a third port fluidly connected to a third pump in the dialysate mixing circuit, the third port connected to an acid flow line, the acid flow line arranged to convey an acid solution from an acid source to the third pump;
• and
• a bypass connector comprising three fluid prongs configured to connect with the first, the second, and the third ports;
• wherein channels in each of the three fluid prongs of the bypass connector terminate within a common chamber within the bypass connector, so that the bicarbonate charge line and the first pump, the bicarbonate return line and the second pump, and the acid flow line and the third pump are fluidly connected to each other upon connection of the bypass connector to the first, the second, and the third ports.