Therapeutic multi-peptides t specific immune therapy for treatment of brain metastasis
AssigneeOse Immunotherapeutics
InventorDOMINIQUE COSTANTINI
Life of this patent
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Abstract
The present invention relates to a peptide vaccine composition OSE-2101 for treatment of brain metastasis in HLA-A2 positive patients.
Claims12
1-11. (canceled)
A method of treating brain metastasis in a HLA-A2 (Human Leukocyte Antigen A2) positive patient comprising the administration to a patient having a brain metastasis of a composition comprising T specific immune therapy peptides RLLQETELV (SEQ ID No 1), YLQLVFGIEV (SEQ ID No 2), LLTFWNPPV (SEQ ID No 3), KVFGSLAFV (SEQ ID No 4), KLBPVQLWV (SEQ ID No 5, with B indicating α-aminoisobutyric acid), SMPPPGTRV (SEQ ID No 6), IMIGHLVGV (SEQ ID No 7), KVAEIVHFL (SEQ ID No 8), YLSGADLNL (SEQ ID No 9), and aKXVAAWTLKAAa (SEQ ID No 10, with X and a respectively indicating cyclohexylalanine and d-alanine).
Dependencies are inferred from the claim text.