Maspin-based inhibition of osteoclast activity and promotion of bone formation
AssigneeNorthwestern University
InventorMing Zhang
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Abstract
Provided herein are compositions and methods for the treatment of bone disorders through the maspin-based inhibition of osteoclastogenesis and osteoclast activity and the promotion of bone formation.
Claims19
A method of treating a bone disorder in a subject comprising administering to the subject an agent that enhances maspin expression, level, and/or activity within the subject.
A method of facilitating bone growth in a subject comprising increasing the level of maspin and/or maspin-based peptides or polypeptides within the subject.
A pharmaceutical composition comprising an active agent that enhances expression, level, or activity of maspin within a subject.
(canceled)
Dependencies are inferred from the claim text.