Formulations and Methods of Administration of Cephalotaxines, Including Homoharringtonine
AssigneeChemGenex Pharmaceuticals, Inc.
InventorDennis Brown
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Abstract
The present invention is directed to compositions and methods for the treatment of patients with cephalotaxines, for example, homoharringtonine. The invention is also directed to improvements in the purity, manufacturing process, formulation and administration of homoharringtonine for the treatment of cancer and other aberrant cellular diseases. The invention also provides methods and compositions for antiparasitic, antifungal, antiviral and antibacterial treatments.
Claims8
-28. (canceled)
An oral dosage form comprising a therapeutically effective dose of homoharringtonine and microcrystalline cellulose.
A liquid dosage form comprising an aqueous solution of homoharringtonine and a pH of about 4.0, wherein the aqueous solution of homoharringtonine exhibits less than a 5% loss of potency as measured by high performance liquid chromatography upon storage for 7 weeks at 60° C.
Dependencies are inferred from the claim text.