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AssigneeNoratech Pharmaceuticals, Inc.
InventorsFei LIU, Cuixia ZHANG, Chenggang LIN, Chunyan ZHOU, Pan CHEN, Wei WANG, Lulu WANG
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The present invention relates to a donepezil derivative of general formula (I) or a pharmaceutically acceptable salt thereof, wherein R in the formula is as disclosed herein; and a method for preparation thereof; and a composition comprising an effective amount of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof. The present invention also relates to use of a compound of the general formula (I) or a pharmaceutically acceptable salt thereof in preparing a medicament for treating a disease resulted from an abnormality in acetylcholinesterase activity.
A compound of formula (I):
A compound or a pharmaceutically acceptable salt thereof, wherein the compound is selected from the group consisting of:
The pharmaceutical composition of claim 8, wherein the excipient is selected from one or more of castor oil, soybean oil, sesame oil, arachis oil, corn oil, cottonseed oil, or glycerides.
Dependencies are inferred from the claim text.