Pharmaceutical compositions containing a pde4 inhibitor and a pi3 delta or dual pi3 delta-gamma kinase inhibitor
AssigneeRhizen Pharmaceuticals SA
InventorsSwaroop K. Vakkalanka, Srikant Viswanadha
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Abstract
This present invention relates to a method of treating a autoimmune, respiratory and/or inflammatory disease or condition (e.g., psoriasis, rheumatoid arthritis, asthma, COPD). The method comprises administering a PI3K Delta inhibitor or a dual PI3K Delta-Gamma inhibitor and a PDE4 inhibitor. The present invention also relates to pharmaceutical compositions containing a PI3K Delta or dual PI3K Delta-Gamma inhibitor and a PDE4 inhibitor.
Claims34
A method of treating an autoimmune, respiratory and/or inflammatory disease or condition, the method comprising administering to a subject in need thereof a therapeutically effective amount of (i) a PI3K Delta inhibitor or a dual PI3K Delta and Gamma inhibitor, and (ii) a PDE4 inhibitor.
A pharmaceutical composition comprising (i) a PI3K Delta or dual PI3K Delta and Gamma inhibitor, or a pharmaceutically acceptable salt thereof, (ii) a PDE4 inhibitor, and (iii) optionally, a pharmaceutically acceptable carrier, glidant, diluent, or excipient.
(canceled)
A kit for treating an autoimmune, respiratory or inflammatory disease or condition, the kit comprising:
- (i) a PI3K Delta or PI3K Delta and Gamma inhibitor, and (ii) a PDE4 inhibitor, either in a single pharmaceutical composition or in separate pharmaceutical compositions,
- (ii) optionally, instructions for treating the autoimmune, respiratory or inflammatory disease or condition with the PI3K Delta or PI3K Delta and Gamma inhibitor, and PDE4 inhibitor, and
- (iii) optionally, a container for placing the pharmaceutical composition or pharmaceutical compositions.
Dependencies are inferred from the claim text.