Novel methods for targeting cancer stem cells
AssigneeBoston Biomedical, Inc.
InventorsChiang Jia Li, David Leggett, Youzhi Li, Wei Li
Life of this patent
Estimating the term…
Abstract
The invention provides naphthofuran compounds, polymorphs of naphthofuran compounds, naphthofuran compounds in particle form, purified compositions that contain one or more naphthofuran compounds, purified compositions that contain one or more naphthofuran compounds in particle form, methods of producing these naphthofuran compounds, polymorphs, purified compositions and/or particle forms, and methods of using these naphthofuran compounds, polymorphs, purified compositions and/or particle forms to treat subjects in need thereof.
Claims6
1-30. (canceled)
A method of treating a cancer in a human subject, the method comprising administering to a subject in need thereof a therapeutically effective amount of a compound having the structure of
- or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof, wherein the compound is administered to the subject at a dose sufficient to achieve a blood concentration of the compound in the subject of at least 1.0 μM or above for at least two hours, and wherein the blood concentration of the compound in the subject is substantially cleared within at most 24 hours.
Dependencies are inferred from the claim text.