System and process for treatment of myopia
AssigneeOjai Retinal Technology, LLC
InventorsJeffrey K. Luttrull, David B. Chang, Benjamin W. L. Margolis
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Abstract
A process for preventing or treating myopia includes applying a pulsed energy, such as a pulsed laser beam, to tissue of an eye having myopia or a risk of having myopia. The source of pulsed energy has energy parameters including wavelength or frequency, duty cycle and pulse train duration, which are selected so as to raise an eye tissue temperature up to eleven degrees Celsius to achieve therapeutic or prophylactic effect, such as stimulating heat shock protein activation in the eye tissue. The average temperature rise of the eye tissue over several minutes is maintained at or below a predetermined level so as not to permanently damage the eye tissue.
Claims19
A process for preventing or treating myopia, comprising the steps of:
- providing a pulsed energy source having energy parameters including wavelength or frequency, duty cycle and pulse train duration, the energy parameters selected so as to raise an eye tissue temperature up to eleven degrees Celsius to achieve a therapeutic or prophylactic effect, wherein the average temperature rise of the eye tissue over several minutes is maintained at or below a predetermined level so as to not permanently damage the eye tissue;
- and
- applying the pulsed energy to tissue of an eye having myopia or a risk of having myopia to stimulate heat shock protein activation in the eye tissue.
The process of claim 9, wherein the pulsed light beam has a power between 0.5 and 74 watts.
A process for preventing or treating myopia, comprising the steps of:
- providing a pulsed energy source having energy parameters including wavelength or frequency, duty cycle and pulse train duration, the energy parameters selected so as to achieve a therapeutic or prophylactic effect while not permanently damage eye tissue;
- determining that an eye has myopia or is at a risk of having myopia;
- and
- applying the pulsed energy to retinal and/or foveal tissue of the eye determined to have myopia or a risk of having myopia to stimulate heat shock protein activation in the eye tissue;
- wherein the pulsed energy is applied to a plurality of eye tissue areas, and wherein adjacent eye tissue areas are separated by at least a predetermined distance to avoid thermal tissue damage;
- and
- wherein the pulsed energy comprises a pulsed light beam having a wavelength between 530 nm to 1300 nm, a duty cycle of less than 10%, and a pulse train duration between 0.1 and 0.6 seconds.
A process for preventing or treating myopia, comprising the steps of:
- providing a pulsed energy source having energy parameters including wavelength or frequency, duty cycle and pulse train duration, the energy parameters selected so as to achieve a therapeutic or prophylactic effect while not permanently damage eye tissue;
- determining that an eye has myopia or is at a risk of having myopia;
- and
- applying the pulsed energy to retinal and/or foveal tissue of the eye determined to have myopia or a risk of having myopia to stimulate heat shock protein activation in the eye tissue;
- wherein the pulsed energy is applied to a plurality of eye tissue areas, and wherein adjacent eye tissue areas are separated by at least a predetermined distance to avoid thermal tissue damage;
- wherein the pulsed energy is applied to a first eye tissue area and, after a predetermined period of time within a single treatment session, the pulsed energy is reapplied to the first eye tissue area, and during an interval between pulsed energy applications to the first eye tissue area the pulsed energy is applied to a second eye tissue area;
- wherein the applying step includes the step of raising the eye tissue temperature between six degrees Celsius to eleven degrees Celsius at least during application of the pulsed energy source while maintaining an average eye tissue temperature rise at approximately one degree Celsius or less over several minutes;
- and
- wherein the pulsed energy comprises a pulsed light beam having a wavelength between 53nm to 1300 nm, a duty cycle of between 2.5% and 5%, a power between 0.5 and 74 watts, and a pulse train duration between 0.1 and 0.6 seconds.
Dependencies are inferred from the claim text.