Drug-eluting stent
AssigneeJimro Co., Ltd.
InventorMatsuya MANABE
Life of this patent
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Abstract
A drug-eluting stent whose main body is made of a metal or a polymeric material, the surface of which is coated with a mixture including cilostazol and a bioabsorbable polymer, wherein the molecular weight of the bioabsorbable polymer is 40,000 to 600,000.
Claims13
1-12. (canceled)
A drug-eluting stent having a net-like main body which is made of a metal or a polymeric material and has flection sections, the surface of which is coated with a mixture comprising cilostazol and a bioabsorbable polymer, wherein the bioabsorbable polymer comprises
- (a) a polymer comprising DL lactide and glycolide in a weight ratio of 7:3-9:1, whose molecular weight is 40,000-400,000,
- (b) a polymer comprising DL lactide whose molecular weight is 50,000-100,000,
- (c) a polymer comprising L lactide and DL lactide in a weight ratio of 6:4-8:2, whose molecular weight is 300,000-600,000,
- (d) a polymer comprising L lactide whose molecular weight is 50,000-150,000, or
- (e) a polymer comprising L lactide and caprolactone in a weight ratio of 6:4-8:2, whose molecular weight is 150,000-400,000.
A process for preparing a drug-eluting stent having a net-like main body which is made of a metal or a polymeric material and has flection sections by coating the surface of the stent with a mixture comprising cilostazol and a bioabsorbable polymer through ultrasonic spraying, wherein the bioabsorbable polymer comprises
- (a) a polymer comprising DL lactide and glycolide in a weight ratio of 7:3-9:1, whose molecular weight is 40,000-400,000,
- (b) a polymer comprising DL lactide whose molecular weight is 50,000-100,000,
- (c) a polymer comprising L lactide and DL lactide in a weight ratio of 6:4-8:2, whose molecular weight is 300,000-600,000,
- (d) a polymer comprising L lactide whose molecular weight is 50,000-150,000, or
- (e) a polymer comprising L lactide and caprolactone in a weight ratio of 6:4-8:2, whose molecular weight is 150,000-400,000.
Dependencies are inferred from the claim text.