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US 2017/0319358 A1Published application
Method and device for producing a three-dimensional, multi-cell object
AssigneeTechnische Universitaet Berlin
InventorLutz KLOKE
Life of this patent
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Abstract
A method for producing a three-dimensional, multi-cell object, in which polymerized structures are produced in layers by the irradiation of light radiation. To this end, use is made of photopolymerizable liquids which at least partly comprise biological cells. The invention also relates to a device for carrying out such a method and to the use of this device for producing an artificial organ.
Claims15
A method for producing a three-dimensional, multi-cell object, comprising the following steps:
- a) introducing a first photopolymerizable liquid into a reaction vessel,
- b) focusing a first light beam on a first focal plane that lies within an area of the reaction vessel filled with the first liquid,
- c) producing a first polymerized structure in a first layer in the reaction vessel by way of the first light beam,
- d) introducing a further photopolymerizable liquid into the reaction vessel, so that a previously produced polymerized structure is at least partially covered with the further photopolymerizable liquid,
- e) focusing a further light beam on a further focal plane that lies within an area of the reaction vessel filled with the further liquid,
- f) producing a further polymerized structure in a further layer in the reaction vessel by way of the further light beam, wherein the further polymerized structure is arranged directly on the previously produced polymerized structure and is connected thereto,
- g) repeating steps d) through f) with one further photopolymerizable liquid each until the three-dimensional multi-cell object is produced,
- wherein the first photopolymerizable liquid and/or at least one of the further photopolymerizable liquids contain biological cells.
5 more elements
A device for producing a three-dimensional, multi-cell object from photopolymerizable liquids, with
- a reaction vessel,
- a light source, which is arranged such that during operation of the device, it can irradiate light in a focal plane into the reaction vessel,
- a reservoir for different photopolymerizable liquids,
- a pump that can be brought into fluid communication with the reservoir and the reaction vessel in order to introduce the different photopolymerizable liquids into the reaction vessel and discharge them from the reaction vessel, and
- a control unit for controlling the light source and the pump.
2 more elements
(canceled)
Dependencies are inferred from the claim text.