Method of selectively killing cancer cells using low-temperature plasma jet device and method of treating tumors using the same
AssigneeDong-A University Research Foundation for Industry-Academy Cooperation
InventorsTae-Hong KANG, Ji-Ye CHOI
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Abstract
A method of selectively killing cancer cells uses a low-temperature plasma jet device. When cancer cells are simultaneously treated with ATR and PARP-1 inhibitors, followed by synchronization of a circadian rhythm and treatment with low-temperature atmospheric-pressure plasma, cancer cell death may be maximized about ten-fold or more compared to when treated with existing low-temperature atmospheric-pressure plasma alone, and thus this method may be usefully used as a future tumor treatment method.
Claims15
A method of selectively killing cancer cells, the method comprising:
- a first process of treating cancer cells with a kinase inhibitor;
- a second process of synchronizing a circadian rhythm of normal cells;
- and
- a third process of controlling exposure conditions of low-temperature atmospheric-pressure plasma generated by a low-temperature atmospheric-pressure plasma generating apparatus using an alternating current power source when the cancer cells of the first process and the normal cells of the second process are cultured.
A method of treating tumors, the method comprising:
- a first process of administering a kinase inhibitor to an animal with a tumor and synchronizing a circadian rhythm of normal cells;
- and
- a second process of treating the animal with low-temperature atmospheric-pressure plasma generated by a low-temperature atmospheric-pressure plasma generating apparatus after the first process.
Dependencies are inferred from the claim text.