An Anticonvulsant Compound
AssigneeRoyal Holloway and Bedford New College
InventorsRobin WILLIAMS, Matthew WALKER
Life of this patent
Estimating the term…
Abstract
The invention relates to pharmaceutical uses of compounds of formula (II). Particular aspects of the invention relate to the use of those compounds in treating, preventing or ameliorating a seizure-related disorder, bipolar disorder, mania, migraine, Alzheimer's disease, Parkinson's disease or stroke.
Claims26
(canceled)
A method of treating, preventing or ameliorating a seizure-related disorder, bipolar disorder, mania, migraine, Alzheimer's disease, Parkinson's disease or stroke, the method comprising administering, to a subject in need of such treatment, a therapeutically effective amount of a compound of formula (II):
- wherein:
- R1 is a carboxylic acid, amide or amine;
- Ring is selected from one of formulae (i) to (xi):
- and
- R2 is an optionally substituted straight or branched alkyl or alkenyl group with 1 to 20 C atoms, and wherein the backbone of the alkyl or alkenyl group is optionally interrupted by one or more heteroatoms.
(canceled)
(canceled)
(canceled)
(canceled)
A compound selected from [4-(4-methylpentyl)cyclohexyl]acetic acid;
- [4-(3-methylpentyl)cyclohexyl]acetic acid;
- 4-(3-methylbutyl)cyclohexanecarboxylic acid;
- 4-(2-methylbutyl)cyclohexanecarboxylic acid;
- [4-(2-methylpentyl)cyclohexyl]acetic acid;
- 4-[(1E)-but-1-en-1-yl]cyclohexanecarboxylic acid;
- (4-pentylidenecyclohexyl)acetic acid;
- 4-(propoxymethyl)cyclohexyl acetic acid;
- 5-butylpiperidine-2-carboxylic acid;
- {4-[(ethylamino)methyl]cyclohexyl}acetic acid;
- 4-(ethoxymethyl)cyclohexancarboxylic acid;
- and 4-propoxycyclohexanecarboxylic acid.
(canceled)
Dependencies are inferred from the claim text.