Inhalation device for use in aerosol therapy of respiratory diseases
AssigneesAblynx N.V., Vectura Limited
InventorsKoen ALLOSERY, Martin HUBER, Tobias KOLB, Bernhard MÜLLINGER, Juliane SCHICK, Erik DEPLA
Life of this patent
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Abstract
An inhalation device, assembly or system can include a kit and a pharmaceutical composition. The device can be adapted for administering therapeutic aerosols to pediatric patients, including neonates, infants or toddlers. The device can further include a vibrating mesh aerosol generator that can be insertable into a flow channel of the inhalation device through a lateral opening, and a valved face mask. The device can be connectable to a gas source through which a gas, such as oxygen, can be received into the flow channel at a low flow rate.
Claims22
An inhalation device for delivering a nebulised aerosol to a patient, the inhalation device comprising:
- (a) an aerosol generator with a vibratable mesh;
- (b) a reservoir for a liquid to be nebulised, said reservoir being in fluid connection with the vibratable mesh;
- (c) a gas inlet opening shaped as a tube fitting;
- (d) a face mask, having:
- a casing,
- an aerosol inlet opening,
- a patient contacting surface, and
- a one-way exhalation valve or a two-way inhalation/exhalation valve in the casing having an exhalation overpressure resistance selected in the range from 0.5 to 5 mbar;
- and
- (e) a flow channel extending from the gas inlet opening to the aerosol inlet opening of the face mask, the flow channel having:
- a lateral opening through which the aerosol generator is at least partially inserted into the flow channel, and
- a constant flow resistance between the gas inlet opening and the aerosol inlet opening of the face mask at a flow rate of 1 to 20 L/min,
- wherein the flow channel upstream of the lateral opening is shaped such as to effect a laminar flow when a gas is conducted through the flow channel at a flow rate from 1 to 20 L/min.
(canceled)
22-28. (canceled)
Dependencies are inferred from the claim text.