Implantable medical device for minimally-invasive insertion

A containment device, comprising:

• a microchip element comprising one or more containment reservoirs that are configured to be electrically activated to open;
• a silicon substrate positioned adjacent to the microchip element;
• one or more electronic components disposed within the silicon substrate, wherein the one or more electronic components are in communication with the microchip element;
• and
• a first inductive coupling device incorporated within the microchip element or within the silicon substrate, wherein the first inductive coupling device is in communication with the one or more electronic components.

An implantable drug delivery device, comprising:

• a microchip element which comprises one or more containment reservoirs that contain a drug payload and that are configured to be electrically activated to open;
• a silicon substrate positioned adjacent to and fixed to the microchip element;
• one or more electronic components disposed within the silicon substrate, wherein the one or more electronic components are in communication with the microchip element;
• and
• a first inductive coupling device incorporated within the microchip element or within the silicon substrate, wherein the first inductive coupling device is in communication with the one or more electronic components,
• wherein:
• the device does not include a header or feedthrough for connecting the microchip element to the PCB,
• the microchip element and the silicon substrate are not contained in a housing, and
• a ratio of a volume of the drug payload to a total volume of the device is from about 75 μL/cc to about 150 μL/cc.