Implantable medical device for delivering cells
AssigneeDeepScience Ltd.
InventorDahl Winters
Life of this patent
Estimating the term…
Abstract
An implantable and retrievable medical device is provided. The device may be implanted in and extracted from a patient and the device is adapted to house and deliver donor cells or other drugs. The device comprises a hollow core having a volume for receiving cells and a plurality of layers surrounding the core. The layers comprise various materials suitable for enhancing immunoprotection and for promoting vascular growth into the device.
Claims20
An implantable cell delivery device adapted to be inserted into the tissue of an animal, the device comprising:
- a shell comprising a core operable to receive and store cells and a first layer provided to enhance immunoprotection and limit fibrosis;
- a second layer comprising an alginate polyacrylamide layer and having a stiffness;
- and
- a third layer comprising a vascularization inducer to promote the growth of new blood vessels to the device.
An implantable cell delivery device adapted to be inserted into the tissue of an animal, the device comprising:
- a sheet comprising a plurality of implants bonded together with alginate-polyacrylamide;
- wherein each of the plurality of implants comprises a core operable to receive and store cells and a first layer provided to enhance immunoprotection and limit fibrosis, a second layer comprising an alginate polyacrylamide layer and having a stiffness;
- and a third layer comprising a vascularization inducer;
- and
- wherein the sheet is operable to be rolled or folded for implantation within an animal.
A method of implanting a cell delivery device in an animal, the method comprising:
- providing an implantable cell delivery device comprising:
- a shell comprising a core operable to receive and store cells and a first layer provided to enhance immunoprotection and limit fibrosis;
- a second layer comprising an alginate polyacrylamide layer;
- and a third layer operable to promote the growth of new blood vessels to the cell delivery device;
- forming an incision in the dermis of an animal;
- implanting the cell delivery device within the incision and such that the cell delivery device is provided subcutaneously in the animal;
- closing the incision and allowing the cell delivery device to remain in the animal, wherein the cell delivery device is operable to promote vascularization induction between the animal and at least one of the first layer, the second layer, and the third layer.
Dependencies are inferred from the claim text.