Microfabricated tissue scaffolds and methods of making and using the same
AssigneeTara Biosystems Inc.
InventorsMiles Montgomery, Boyang Zhang, Milica Radisic
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Abstract
The present description relates to the discovery of materials, devices, systems and methods for microfabrication of engineered tissue scaffolds for the growth and culture of biological tissues for tissue repair, transplantation, disease treatment, regenerative medicine, drug testing or combinations thereof. The engineered tissue scaffolds mimic native conditions and structures, including, e.g., native physiology, tissue architecture, vasculature, and other properties of native tissues.
Claims22
A shape-memory polymer fiber tissue scaffold comprising micro- or nano-sized elastomeric fibers or a combination thereof, wherein the fibers are arranged into a reversibly deformable design or configuration.
A tissue scaffold system comprising an interlocking polymer fiber layer comprising micro- or nano-sized elastomeric fibers or a combination thereof, wherein the fiber layer has a top surface and a bottom surface, and includes an array of micro-hooks extending from at least one surface.
Dependencies are inferred from the claim text.