METHODS OF USING ANTI-CD79b IMMUNOCONJUGATES
AssigneeGenentech, Inc.
InventorsAndrew Polson, Shang-Fan Yu, Yu-Waye Chu, Michael Wenger
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Abstract
Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
Claims41
A method for treating a B-cell proliferative disorder in an individual comprising administering to the individual an effective amount of (a) an immunoconjugate comprising an anti-CD79b antibody linked to a cytotoxic agent, (b) an anti-CD20 antibody, and (c) a BCL-2 inhibitor.
A method of treating relapsed/refractory diffuse large B-cell lymphoma in an individual comprising administering to the individual an effective amount of (a) polatuzumab vedotin, and (b) obinutuzumab, and (c) venetoclax.
A method of treating relapsed/refractory follicular lymphoma in an individual comprising administering to the individual an effective amount of (a) polatuzumab vedotin, and (b) obinutuzumab, and (c) venetoclax.
Dependencies are inferred from the claim text.