Compositions and Methods for Immunizing Against C. Difficile
AssigneeSanofi Pasteur Limited
InventorsPatricia Pietrobon, Ginamarie Foglia, Guy De Bruyn, Sanjay Gurunathan
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Abstract
This disclosure relates to methods for eliciting an immune response against C. difficile toxin A and toxin B in an adult human subject. The subject may be at risk for a primary symptomatic C. difficile infection. In some embodiments, a method is for eliciting an immune response against C. difficile toxin A and toxin B in an adult human subject at risk for a primary symptomatic C. difficile infection, and comprises administering to the subject a composition comprising C. difficile toxoid A and toxoid B at least three times, each administration being about seven days apart.
Claims37
A method for eliciting an immune response against C. difficile toxin A and toxin B in an adult human subject at risk for a primary symptomatic C. difficile infection, the method comprising administering to the subject a composition comprising C. difficile toxoid A and toxoid B at least three times, each administration being about seven days apart.
Using a composition comprising C. difficile toxoid A and toxoid B in producing a medicament for eliciting an immune response against C. difficile toxin A and toxin B in an adult human subject at risk for a primary symptomatic C. difficile infection by administering the composition to the subject at least three times, each administration being about seven days apart.
A composition comprising C. difficile toxoid A and toxoid B for use in a method for eliciting an immune response against C. difficile toxin A and toxin B in a human subject, the method comprising administering the subject the composition at least three times, each administration being about 7 days apart.
Dependencies are inferred from the claim text.