Orally disintegrating solid pharmaceutical dosage unit containing a partus control substance
AssigneeOxytone Bioscience B.V.
InventorsJohannes Jan PLATTEEUW, Herman Jan Tijmen COELINGH BENNINK
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AssigneeOxytone Bioscience B.V.
InventorsJohannes Jan PLATTEEUW, Herman Jan Tijmen COELINGH BENNINK
Estimating the term…
An orally disintegrating solid pharmaceutical dosage unit having a weight between 50 and 1,000 mg is disclosed. The dosage unit consists of: (a) 5-100 wt. % of coated particles comprising 50-99 wt. % of a core particle and 1-50 wt. % of a coating that envelops the core particle, said coating consisting of: 0.01-10 wt. % of a partus control substance selected from oxytocin, carbetocin, atosiban and combinations thereof; 5-50 wt. % of buffering agent; 15-80 wt. % of branched glucan; 0-78 wt. % of other pharmaceutically acceptable ingredients; and (b) 0-95 wt. % of one or more pharmaceutically acceptable excipients; the solid dosage unit comprising at least 20 μg of the partus control substance and having a pH buffer range of 3.5-5.7.
-15. (canceled)
An orally disintegrating solid pharmaceutical dosage unit having a weight between 50 and 1,000 mg and comprising:
Dependencies are inferred from the claim text.