Use of alphavirus in preparation of antitumor drugs
AssigneeGuangzhou Virotech Pharmaceutical Co., Ltd.
InventorsGuangmei YAN, Xiao XIAO, Jun HU, Kai LI, Jiankai LIANG, Yuan LIN, Haipeng ZHANG, Suizhen LIN
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Abstract
Disclosed is use of alphavirus in preparation of antitumor drugs. The alphavirus is M1 virus or Getah virus. In addition, the specific tumor types sensitive to abovementioned alphavirus treatment are further determined, so as to provide a safe and effective solution for antitumor drug administering schemes.
Claims17
1-10. (canceled)
A method of treating a subject, preferably a human subject with tumor, comprising administering to the subject at least one alphavirus, wherein said alphavirus is selected from an M1 virus and a Getah virus.
An antitumor administrating system, comprising a ZAP expression level detecting reagent and at least one alphavirus, wherein the alphavirus is selected from an M1 virus and a Getah virus.
An antitumor medicament, comprising at least one alphavirus and ZAP inhibitor(s), wherein the alphavirus is selected from an M1 virus and a Getah virus.
Dependencies are inferred from the claim text.