Method of activating lactic acid bacteria
AssigneeInfant Bacterial Therapeutics AB
InventorsStaffan Strömberg, Eamonn Connolly, Stefan Roos
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Abstract
The present invention relates to methods of activating live lactic acid bacteria comprising exposing said bacteria to a preparation comprising citrate, wherein said bacteria have the ability to utilize citrate as an external electron acceptor. The present invention further relates to methods to enhance the activity of certain live bacteria in mammals. More specifically the invention relates to improve the wake-up of certain lactic acid bacteria from the freeze-dried state. The present invention also relates to preparations comprising said activated bacteria and therapeutic uses of said activated bacteria.
Claims28
1-34. (canceled)
A method of treating of a subject having a condition benefiting from the administration of faster activated live bacteria or bacteria with an improved growth rate, comprising:
- administering to the subject a therapeutically effective amount of citrate activated lactic acid bacteria,
- wherein the citrate activated lactic acid bacteria utilizes citrate as an external electron acceptor, thereby treating the subject having a condition benefiting from the administration of faster activated live bacteria or bacteria with an improved growth rate.
A method of treating of a subject having a condition benefiting from the administration of faster activated live bacteria or bacteria with an improved growth rate, comprising:
- administering to the subject a therapeutically effective amount of (i) a lactic acid bacteria that utilizes citrate as an external electron receptor and (ii) citrate, wherein the lactic acid bacteria is activated by the citrate,
- thereby treating the subject having a condition benefiting from the administration of faster activated live bacteria or bacteria with an improved growth rate.
Dependencies are inferred from the claim text.