Compositions and methods for treating viral hemorrhagic fever
AssigneeCerus Corporation
InventorLaurence CORASH
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Abstract
The present disclosure provides compositions and methods for the treatment of viral hemorrhagic fever. The compositions and methods are useful for treating hemorrhagic fever virus infections and conditions associated with such infections.
Claims121
A method of treating a subject suffering from a hemorrhagic fever virus infection, comprising administering to the subject a therapeutically effective amount of a plasma, wherein the plasma comprises a first plasma component obtained from one or more plasma donors previously infected with the same type of hemorrhagic fever virus and a second plasma component obtained from one or more plasma donors not previously infected with the same type of hemorrhagic fever virus.
A method of treating a condition associated with a hemorrhagic fever virus infection in a subject, comprising administering a plasma in an amount effective to treat coagulopathy or endothelial cell dysfunction, wherein the plasma comprises donor plasma obtained from one or more donors previously infected with or immunized against the same type of hemorrhagic fever virus, and wherein the plasma or donor plasma is treated with a pathogen inactivation compound to inactivate pathogens, if present.
Dependencies are inferred from the claim text.