Oral iodine dosage form
AssigneeBioPharmX, Inc.
InventorsRussell P. Elliott, Douglas W. Thomas, Akira Yamamoto
Life of this patent
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Abstract
Provided is an oral dosage form comprising a deliverable form of iodine for treating symptoms related to fibrocystic breast condition, for prophylactically maintaining breast health, for treating fibrocystic breasts or breast cancer in pre-menopausal women, for prophylactically maintaining prostate health, and for treating benign prostate hyperplasia along with related methods for making and administering such dosage form. More particularly, this disclosure relates to an oral dosage form that is effective to deliver supraphysiologic levels of molecular iodine. The oral dosage form generally comprises a source of iodine and a reactive agent, wherein the source of iodine and/or the reactive agent are provided in excess.
Claims31
An oral dosage form comprising
- a source of iodine, and
- a reactive agent, wherein
- (i) the total iodine in the oral dosage form is 3 to 60 milligrams,
- (ii) the source of iodine reacts with the reactive agent in simulated gastric fluid to form molecular iodine, and
- (iii) the amount of at least one of the source of iodine or the reactive agent is present in excess of the stoichiometric amount required for the reaction to form molecular iodine.
A method for fabricating an oral dosage form comprising the steps of
- (i) providing a source of iodine,
- (ii) providing a reactive agent, and
- (iii) combining the source of iodine and the reactive agent to form an oral dosage form with an effective pH above 7,
- wherein either the source of iodine or the reactive agent is provided in excess of the corresponding molar ratio for the reaction(s) to form molecular iodine.
Dependencies are inferred from the claim text.