Pharmaceutical composition for treating a viral infection
AssigneeLondon School of Hygiene and Tropical Medicine
InventorPolly Roy
Life of this patent
Estimating the term…
Abstract
The invention concerns a pharmaceutical composition for treating a viral infection caused by a member of the Reoviridae family; a method of treatment involving the use of same and use of the anti-viral to treat said viral infection. The agent has use in both humans and animals.
Claims27
A pharmaceutical composition effective against a member of the Reoviridae virus family comprising:
- at least one oligonucleotide complementary to an untranslated region (UTR) of a nucleic acid located, either 5′ or 3′, adjacent a coding region of at least one viral genome segment& that constitutes a viral genome;
- and
- at least one pharmaceutically acceptable carrier.
The pharmaceutical composition according to claim 9 wherein said oligonucleotide is modified to replace 2′OH of each ribose with 2′O-methyl.
A method for preparing a pharmaceutical composition comprising bringing an oligonucleotide complementary to an untranslated region (UTR) of nucleic acid located, either 5′ or 3′, adjacent the coding region of at least one viral genome segments that constitutes the viral genome in conjunction or association with a pharmaceutically or veterinarily acceptable carrier or vehicle.
-30. (canceled)
Dependencies are inferred from the claim text.