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US 2017/0304333 A1Published application
Iminosugars and methods of treating viral diseases
AssigneesEmergent Virology LLC, The Chancellor, Masters and Scholars of the University of Oxford
InventorsUrban RAMSTEDT, Brennan KLOSE, Nicole Zitzmann, Raymond A. Dwek, Terry D. Butters
Life of this patent
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Abstract
Provided are methods of treating or preventing viral infections caused by or associated with a Dengue virus using iminosugars.
Claims22
-21. (canceled)
A method of treating a Dengue viral infection comprising administering to a human subject in need thereof an effective amount of a compound of formula:
- wherein:
- W1-4 are independently selected from hydrogen, alkyl groups, haloalkyl groups, alkanoyl groups, aroyl groups, or haloalkanoyl groups;
- and
- R is an alkyl group or an oxaalkyl group.
1 more element
A method of treating a Dengue viral infection comprising administering to a human subject in need thereof an effective amount of a compound of formula:
- wherein:
- W1-4 are independently selected from hydrogen, alkyl groups, haloalkyl groups, alkanoyl groups, aroyl groups, or haloalkanoyl groups;
- and
- R is
- wherein:
- R1 is an alkyl group;
- X1-5 are independently selected from H, NO2, N3, or NH2;
- Y is absent or is a C1-alkyl group, other than carbonyl;
- and
- Z is selected from a bond or NH;
- provided that when Z is a bond, Y is absent, and provided that when Z is NH, Y is a C1-alkyl group, other than carbonyl.
8 more elements
Dependencies are inferred from the claim text.