Topical oily foam compositions
AssigneePerrigo Israel Pharmaceuticals Ltd.
InventorsMichal N. Arnon, Tatiana Kamenetsky
Life of this patent
Estimating the term…
Abstract
Topical alcohol-free thermo labile oily foam composition comprising (i) at least one active pharmaceutical ingredient or ectoparasitic active ingredient; (ii) at least about 20% w/w of at least one lipophilic component; (iii) at least about 10% w/w of at least one non-ionic surfactant; (iv) at least about 0.5% w/w of at least one fatty alcohol or fatty acid or ester thereof with melting point above 30° C., and; (v) at least about 7% w/w of propellant selected from propane, butane, isobutane and combinations thereof; said composition optionally comprising at least about 5% to about 70% w/w of a hydrophilic component, optionally comprising up to about 5% w/w hydrogenated oil and optionally comprising a penetration enhancer.
Claims17
1-9. (canceled)
A method of treating, alleviating or preventing at least one of (i) a dermatological or mucosal disease or disorder and, (ii) ectoparasitosis, comprising topically administering to a subject in need thereof an effective amount of a topical alcohol-free thermo labile oily foam composition, the composition comprising
- (i) at least one active pharmaceutical ingredient or ectoparasitic active ingredient;
- (ii) at least about 20% w/w of at least one lipophilic component;
- (iii) at least about 10% w/w of at least one non-ionic surfactant;
- (iv) at least about 0.5% w/w of at least one fatty alcohol or fatty acid or ester thereof with melting point above 30° C., and;
- (v) at least about 7% w/w of propellant selected from propane, butane, isobutane and combinations thereof;
- said composition optionally comprising at least about 5% to about 70% w/w of a hydrophilic component, optionally comprising up to about 5% w/w hydrogenated oil and optionally comprising a penetration enhancer;
- and wherein the composition is a readily collapsible foam composition.
A method of treating, alleviating or preventing at least one of (i) a dermatological or mucosal disease or disorder and, (ii) ectoparasitosis, comprising topically administering to a subject in need thereof a therapeutically effective amount of the topical alcohol-free thermo labile oily foam composition comprising:
- (i) at least one active pharmaceutical ingredient or ectoparasitic active ingredient;
- (ii) at least about 20% w/w of at least one lipophilic component;
- (iii) at least about 10% w/w of at least one non-ionic surfactant;
- (iv) at least about 0.5% w/w of at least one fatty alcohol or fatty acid or ester thereof with melting point above 30° C., and;
- (v) at least about 7% w/w of propellant selected from propane, butane, isobutane and combinations thereof;
- said composition optionally comprising about 5 to about 70% w/w of a hydrophilic component and optionally comprising up to about 5% w/w hydrogenated oil;
- and wherein the composition is a readily collapsible foam composition.
A method for topically delivering a therapeutically effective amount of an active pharmaceutical ingredient or ectoparasitic active ingredient by topically applying a therapeutically effective amount of a topical alcohol-free thermo labile oily foam composition to a subject in need thereof, the composition comprising
- (i) at least one active pharmaceutical ingredient or ectoparasitic active ingredient;
- (ii) at least about 20% w/w of at least one lipophilic component;
- (iii) at least about 10% w/w of at least one non-ionic surfactant;
- (iv) at least about 0.5% w/w of at least one fatty alcohol or fatty acid or ester thereof with melting point above 30° C., and;
- (v) at least about 7% w/w of propellant selected from propane, butane, isobutane and combinations thereof;
- said composition optionally comprising at least about 5% to about 70% w/w of a hydrophilic component, optionally comprising up to about 5% w/w hydrogenated oil and optionally comprising a penetration enhancer;
- and wherein the composition is a readily collapsible foam composition.
20-27. (canceled)
A method of treating, alleviating or preventing at least one of (i) a dermatological or mucosal disease or disorder comprising topically administering to a subject in need thereof a therapeutically effective amount of the topical alcohol-free thermo labile oily foam composition comprising:
- (i) at least one active pharmaceutical ingredient;
- (ii) at least about 20% w/w of at least one lipophilic component;
- (iii) at least about 10% w/w of at least one non-ionic surfactant;
- (iv) at least about 0.5% w/w of at least one fatty alcohol or fatty acid or ester thereof with melting point above 30° C., and;
- (v) at least about 7% w/w of propellant selected from propane, butane, isobutane and combinations thereof;
- said composition optionally comprising about 5 to about 70% w/w of a hydrophilic component and optionally comprising up to about 5% w/w hydrogenated oil;
- and wherein the composition is a readily collapsible foam composition.
(canceled)
Dependencies are inferred from the claim text.