Intranasal pharmaceutical dosage forms comprising naloxone
AssigneeEuro-Celtique S.A.
InventorsJohn STRANG, Alexander OKSCHE, Stephen HARRIS, Kevin SMITH, Lucie Helene Jeanne MOTTIER
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Abstract
The present invention relates to an intranasal pharmaceutical dosage form comprising a dosing unit comprising naloxone or a pharmaceutically acceptable salt thereof in an amount of equivalent to ≧0.5 mg naloxone HCl dissolved in an application fluid of a volume of ≦250 μl. Furthermore, the present invention relates to such an intranasal pharmaceutical dosage form for use in the treatment of opioid overdosing and/or at least one symptom thereof.
Claims18
1-21. (canceled)
A method of treating opioid overdosing or at least one symptom thereof, the method comprising intranasally administering to a patient in need thereof 100 μl of an intranasal pharmaceutical dosage form comprising naloxone or a pharmaceutically acceptable salt thereof dissolved in an application fluid in a final concentration equivalent to between 13 mg naloxone HCl per ml application fluid and 66 mg naloxone HCl per ml application fluid.
Dependencies are inferred from the claim text.