Peptides and Their Use in the Treatment of Skin
AssigneeAvon Products, Inc.
InventorsJolanta Idkowiak-Baldys, John W. Lyga, Uma Santhanam
Life of this patent
Estimating the term…
Abstract
Provided are methods of diminishing the signs of aging and/or improving the health of human integuments, such as skin, and compositions comprising peptides useful therefor. The compositions according to the invention comprise a peptide comprising the sequence selected from LRLK (SEQ ID NO: 1), MVV (SEQ ID NO: 2), TAKDGAP (SEQ ID NO: 3), IFGGTVYRS (SEQ ID NO: 4), and RTPKISKPIKFELSG (SEQ ID NO: 5) or a derivative, or fragment thereof, in a topically acceptable vehicle.
Claims20
A method for improving the health and/or appearance of human skin affected by dermatological signs of aging comprising topically applying to an area of skin in need thereof a composition comprising, in a topically acceptable vehicle, an effective amount of a peptide comprising the sequence selected from the group consisting of LRLK (SEQ ID NO:
- 1), LRL (SEQ ID NO:
- 6), RLK (SEQ ID NO:
- 7), MVV (SEQ ID NO:
- 2), TAKDGAP (SEQ ID NO:
- 3), TAK (SEQ ID NO:
- 8), AKD (SEQ ID NO:
- 9), KDG (SEQ ID NO:
- 10), DGA (SEQ ID NO:
- 11), GAP (SEQ ID NO:
- 12), TAKD (SEQ ID NO:
- 13), AKDG (SEQ ID NO:
- 14), KDGA (SEQ ID NO:
- 15), DGAP (SEQ ID NO:
- 16), IFGGTVYRS (SEQ ID NO:
- 4), IFG (SEQ ID NO:
- 17), FGG (SEQ ID NO:
- 18), GGT (SEQ ID NO:
- 19), GTV (SEQ ID NO:
- 20), TVY (SEQ ID NO:
- 21), VYR (SEQ ID NO:
- 22), YRS (SEQ ID NO:
- 23), IFGG (SEQ ID NO:
- 24), FGGT (SEQ ID NO:
- 25), GGTV (SEQ ID NO:
- 26), GTVY (SEQ ID NO:
- 27), TVYR (SEQ ID NO:
- 28), VYRS (SEQ ID NO:
- 29), RTPKISKPIKFELSG (SEQ ID NO:
- 5), RTP (SEQ ID NO:
- 30), TPK (SEQ ID NO:
- 31), PKI (SEQ ID NO:
- 32), KIS (SEQ ID NO:
- 33), ISK (SEQ ID NO:
- 34), SKP (SEQ ID NO:
- 35), KPI (SEQ ID NO:
- 36), PIK (SEQ ID NO:
- 37), IKF (SEQ ID NO:
- 38), KFE (SEQ ID NO:
- 39), FEL (SEQ ID NO:
- 40), ELS (SEQ ID NO:
- 41), LSG (SEQ ID NO:
- 42), RTPK (SEQ ID NO:
- 43), TPKI (SEQ ID NO:
- 44), PKIS (SEQ ID NO:
- 45), KISK (SEQ ID NO:
- 46), ISKP (SEQ ID NO:
- 47), SKPI (SEQ ID NO:
- 48), KPIK (SEQ ID NO:
- 49), PIKF (SEQ ID NO:
- 50), IKFE (SEQ ID NO:
- 51), KFEL (SEQ ID NO:
- 52), FELS (SEQ ID NO:
- 53), and ELSG (SEQ ID NO:
- 54) for a time sufficient to improve the appearance and/or health of said skin.
A composition comprising an effective amount of a peptide comprising the sequence selected from the group consisting of LRLK (SEQ ID NO:
- 1), LRL (SEQ ID NO:
- 6), RLK (SEQ ID NO:
- 7), MVV (SEQ ID NO:
- 2), TAKDGAP (SEQ ID NO:
- 3), TAK (SEQ ID NO:
- 8), AKD (SEQ ID NO:
- 9), KDG (SEQ ID NO:
- 10), DGA (SEQ ID NO:
- 11), GAP (SEQ ID NO:
- 12), TAKD (SEQ ID NO:
- 13), AKDG (SEQ ID NO:
- 14), KDGA (SEQ ID NO:
- 15), DGAP (SEQ ID NO:
- 16), IFGGTVYRS (SEQ ID NO:
- 4), IFG (SEQ ID NO:
- 17), FGG (SEQ ID NO:
- 18), GGT (SEQ ID NO:
- 19), GTV (SEQ ID NO:
- 20), TVY (SEQ ID NO:
- 21), VYR (SEQ ID NO:
- 22), YRS (SEQ ID NO:
- 23), IFGG (SEQ ID NO:
- 24), FGGT (SEQ ID NO:
- 25), GGTV (SEQ ID NO:
- 26), GTVY (SEQ ID NO:
- 27), TVYR (SEQ ID NO:
- 28), VYRS (SEQ ID NO:
- 29), RTPKISKPIKFELSG (SEQ ID NO:
- 5), RTP (SEQ ID NO:
- 30), TPK (SEQ ID NO:
- 31), PKI (SEQ ID NO:
- 32), KIS (SEQ ID NO:
- 33), ISK (SEQ ID NO:
- 34), SKP (SEQ ID NO:
- 35), KPI (SEQ ID NO:
- 36), PIK (SEQ ID NO:
- 37), IKF (SEQ ID NO:
- 38), KFE (SEQ ID NO:
- 39), FEL (SEQ ID NO:
- 40), ELS (SEQ ID NO:
- 41), LSG (SEQ ID NO:
- 42), RTPK (SEQ ID NO:
- 43), TPKI (SEQ ID NO:
- 44), PKIS (SEQ ID NO:
- 45), KISK (SEQ ID NO:
- 46), ISKP (SEQ ID NO:
- 47), SKPI (SEQ ID NO:
- 48), KPIK (SEQ ID NO:
- 49), PIKF (SEQ ID NO:
- 50), IKFE (SEQ ID NO:
- 51), KFEL (SEQ ID NO:
- 52), FELS (SEQ ID NO:
- 53), and ELSG (SEQ ID NO:
- 54) and a topically acceptable vehicle.
Dependencies are inferred from the claim text.