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US 2017/0304058 A1Published application
Implant for Repairing a Cartilage Defect
AssigneeTetec - Tissue Engineering Technologies Aktiengese
InventorsChristoph Gaissmaier, Juergen Fritz, Wilhelm Aicher
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Abstract
An implant for repairing a cartilage defect comprising a first layer and a second layer. The first layer comprises a membrane-like structure and the second layer comprises a sponge-like structure with directional and/or interconnected pores. The first layer is facing the synovial space and the second layer is located towards bone.
Claims21
An implant for repairing a cartilage defect comprising:
- a first layer comprising a stable scaffolding in the form of a membrane structure;
- and a second layer comprising at least one wettable material and a sponge structure comprising interconnected pores;
- wherein 1) the pores form hollow fiber structures orientated directionally in columns and that run substantially parallel to each other, have a substantially consistent pore size and 2) said first layer faces an opposite direction relative to said second layer and 3) wherein said first layer comprises a material having a resorption time exceeding a resorption time of said second layer.
(canceled)
A method for treating a cartilage defect comprising the steps of:
- a) providing an implant in a vessel, wherein the implant comprises a first and at least a second layer, wherein said first layer comprises a membrane-like structure and said second layer comprises a sponge-like structure having directional and interconnected pores of a size of about 50 μm to about 250 μm and wherein said second layer is adapted to be located at or near the cartilage defect, and wherein the first layer comprises a material having a resorption time exceeding the resorption time of the second layer;
- b) cutting the defect cartilage of a patient with a punching device and subsequent curettage to obtain a defect contact surface;
- c) cutting the implant to the same size as the defect contact surface obtained in step b;
- and
- d) introducing the implant onto the defect contact surface.
2 more elements
A three-dimensional implant for repairing a cartilage defect, comprising;
- a) a first layer comprising a membrane structure comprising stable scaffolding;
- and
- b) a second layer comprising at least one wettable material and a sponge structure comprising interconnected pores, wherein cells are seeded on the sponge structure of the implant, further wherein 1) the pores form hollow fiber structures arranged as columns that run substantially parallel to each other and have a substantially consistent pore size, 2) said first layer is configured to face in one direction towards a synovial space and said second layer is configured to face in an opposed direction towards bone, 3) wherein said first layer comprises a material having a resorption time exceeding a resorption time of said second layer and 4) wherein said first layer is fixed to said second layer through lyophilisation.
Dependencies are inferred from the claim text.