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US 2017/0294608 A1Published application
Self-assembled, electronically-functional nucleic acid nanostructures and networks based on the use of orthogonal base pairs
AssigneeThe Trustees of Columbia University in the City of New York
InventorsSimon Alexander Vecchioni, Samuel (Shalom) Jonas Wind
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Abstract
Methods and systems for engineering a nanostructure are provided. An exemplary method includes creating at least one cytosine-cytosine and/or thymine-thymine mismatch in at least one oligonucleotide sequence, placing a metal ion into the mismatch of the oligonucleotide sequence to form an electronically functionalized nanostructure, and inducing self-assembly of the oligonucleotide sequence into a defined structure.
Claims17
A method for engineering a nanostructure, comprising:
- creating at least one cytosine-cytosine and/or thymine-thymine mismatch in at least one oligonucleotide sequence,
- placing a metal ion into the mismatch of the oligonucleotide sequence to form an electronically functionalized nanostructure, and
- inducing self-assembly of the oligonucleotide sequence into a defined structure.
Dependencies are inferred from the claim text.