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US 2017/0291945 A1Published application
Targeting aneurysm disease by modulating phagocytosis pathways
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsNicholas J. Leeper, Irving L. Weissman
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Abstract
In the methods of the invention, an agent that increases phagocytosis and/or efferocytosis of cellular components of coronary plaque is administered to the subject in a dose and for a period of time effective to stabilize, prevent or reduce aneurysm disease in the individual.
Claims20
A method of treating a subject for aneurysm disease, the method comprising:
- administering to the subject an effective dose of an agent that increases the efferocytosis and/or phagocytosis of components of a diseased vessel wall;
- wherein aneurysm is prevented or stabilized.
Dependencies are inferred from the claim text.