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US 2017/0291944 A1Published application
Jam-c antibodies and methods for treatment of cancer
AssigneeResearch Development Foundation
InventorsBeat IMHOF, Christiane ODY, Thomas MATTHES, Carmen DONATE
Life of this patent
Estimating the term…
Abstract
A novel method to reduce B-cell lymphoma cell migration to and engraftment of the spleen in patients with JAM-C positive B-cell lymphomas is described. In certain aspects, a method for identifying and treating JAM-C positive B-cell lymphoma patients with anti-JAM-C antibodies is provided. Recombinant antibody molecules that specifically bind to JAM-C are also disclosed.
Claims10
-69. (canceled)
A composition comprising a monoclonal antibody, wherein the monoclonal antibody competes successfully for binding a JAM-C positive B-cell with H225, Hj20 or Hj223.3 monoclonal antibody.
Dependencies are inferred from the claim text.