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US 2017/0290954 A1Published application
Compositions and methods for treating spinal cord injury
AssigneeB. G. Negev Technologies and Applications Ltd., At Ben-Gurion University
InventorsSmadar COHEN, Dasa CIZKOVA
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Abstract
The present invention provides a method for treating spinal cord injury and repairing or regenerating a damaged spinal cord tissue comprising administering a composition comprising a sulfated alginate or sulfated hyaluronan optionally affinity-bound to one or more growth factors.
Claims20
A method for repairing or regenerating damaged spinal cord tissue in a subject;
- treating a spinal cord injury in a subject;
- promoting the regrowth of one or more axons in a subject with a spinal cord injury;
- the method comprising the step of:
- administering to said subject a composition comprising a polysaccharide and a polypeptide operably linked to said polysaccharide, wherein said polysaccharide is a sulfated alginate or a sulfated hyaluronan, and wherein said polypeptide is a growth factor, thereby repairing or regenerating said damaged spinal cord tissue in said subject.
1 more element
A method for repairing or regenerating damaged spinal cord tissue in a subject;
- treating a spinal cord injury in a subject;
- or promoting the regrowth of one or more axons in a subject with a spinal cord injury, the method comprising the step of:
- administering to said subject a composition comprising an alginate, alginate sulfate, or hyaluronan sulfate, or a combination thereof, and lacking a bioactive polypeptide, thereby repairing or regenerating said damaged spinal cord tissue in said subject.
Dependencies are inferred from the claim text.