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US 2017/0290951 A1Published application
Self-assembling peptide scaffolds
AssigneesShima Tavakol, Cellular and Molecular Research Center, Iran University of Medical Sciences
InventorsShima Tavakol, Behnaz Tavakol, Amin Almasi, Seyed Mahdi Rezayat Sorkhabadi
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Abstract
A mixture for an injectable scaffold may include a self-assembling core and an additive. The additive may include an angiogenic agent, a small molecule drug, and/or an anti-inflammatory agent. The scaffold can be applied to sites where bone growth is desired.
Claims21
A mixture for an injectable scaffold, the mixture comprising:
- a self-assembling core, and
- an additive;
- wherein the additive is selected from a group consisting of an angiogenic agent, a small molecule drug, an anti-inflammatory agent, and combinations thereof.
A mixture for an injectable scaffold, the mixture comprising:
- a self-assembling core,
- an angiogenic agent,
- a small molecule drug, and
- an anti-inflammatory agent.
1 more element
A method for preparing an in-situ scaffold, the method comprising:
- dissolving a self-assembling core in a solvent to form a first solution;
- preparing a nanoemulsion of Fingolimod;
- mixing the first solution with the nanoemulsion of Fingolimod and an additive to form a second solution;
- and
- applying the second solution to a bone defect site to form a gel as an in-situ scaffold.
2 more elements
Dependencies are inferred from the claim text.