Treatment of infection by human enterovirus d68
AssigneeAnsun Biopharma, Inc.
InventorRonald D. Moss
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Abstract
The present disclosure provides compositions and methods for treating an infection by EV-D68. In particular, the present disclosure provides methods that entail administering agents having an anchoring domain that anchors the compound to the surface of a target cell, and a sialidase domain that can act extracellularly to inhibit infection of a target cell by EV-D68.
Claims24
1-23. (canceled)
A method of treating infection by EV-D68 in a patient, the method comprising administering to the patient an effective amount of an agent having sialidase activity.
A method of reducing the risk of infection by EV-D68 or the severity of infection by EV-D68, the method comprising administering to the patient an effective amount of an agent having sialidase activity.
The method of claim 22 wherein the polypeptide comprises or consists of:
- a) amino acids 274-681 SEQ ID NO:
- 1;
- amino acids 274-666 of SEQ ID NO:
- 12;
- or c) amino acids 290-681 of SEQ ID NO:
- 12.
Dependencies are inferred from the claim text.