US 2017/0290890 A1 · STIMULATION OF OVARIAN FOLLICLE DEVELOPMENT AND OOCYTE MATURATION

Abstract

Methods are provided for stimulating ovarian follicles in a mammal through activation of the mTor signaling pathway.

Dependent claims

A method of promoting the development of mature oocytes, the method comprising:

contacting ovarian tissue in vivo or in vitro with an effective dose of an agent that activates signaling in the mechanistic target of rapamycin (mTor) pathway for a period of time sufficient to promote the development of a mature oocyte.

Dependencies are inferred from the claim text.

Facts

Application

15/508,854Filed 9 Sep 2015

Priority

10 Sep 2014

Published

12 Oct 2017

Term ends

Not estimatedThe source records don’t support an estimate.

A61K 38/24
Hormones: follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
A61K 31/36
Having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel: compounds containing methylenedioxyphenyl groups, e.g. sesamin
A61K 31/365
Having oxygen as the only ring hetero atom, e.g. fungichromin: lactones
A61K 31/53
Having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins: having six-membered rings with three nitrogens as the only ring hetero…

Methods are provided for stimulating ovarian follicles in a mammal through activation of the mTor signaling pathway.

Dependent claims

A method of promoting the development of mature oocytes, the method comprising:

contacting ovarian tissue in vivo or in vitro with an effective dose of an agent that activates signaling in the mechanistic target of rapamycin (mTor) pathway for a period of time sufficient to promote the development of a mature oocyte.

Dependencies are inferred from the claim text.