Methods of treating cancer with tubulysin conjugates
AssigneeEndocyte, Inc.
InventorsChristopher Paul LEAMON, Joseph Anand REDDY, Binh NGUYEN, Alicia BLOOMFIELD, Melissa NELSON, Ryan DORTON
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Abstract
The invention described herein pertains to drug delivery conjugates for targeted therapy. The invention described herein relates to methods of treating folate receptor-expressing cancers with a folate-tubulysin conjugate. The invention described herein also relates to methods of treating folate-expressing cancers with a folate tubulysin conjugate in patients where stable disease results after treatment with the folate-tubulysin conjugate.
Claims28
A method for treating a cancer in a patient in need of such treatment comprising, administering to the patient a therapeutically effective amount of a compound of the formula I
- or a pharmaceutically acceptable salt thereof, wherein the cancer is selected from the group consisting of non-small cell lung cancer, ovarian cancer, pleural mesothelioma, adenocarcinoma of gastroesophogeal junction, leiomyosarcoma and small cell lung cancer.
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Dependencies are inferred from the claim text.