Novel Mensenchymal Stem Cells And Bone-Forming Cells
OwnerCindy Badoer, Enrico Bastianelli +1inventors
InventorsCindy Badoer, Enrico Bastianelli, Xavier Pesesse
Life of this patent
Estimating the term…
Abstract
The invention relates to a new type of mesenchymal stem cells (MSC) which co-express at least one mesenchymal marker, preferably at least CD105 and CD34. Also provided are bone-forming cells having an analogous phenotype. The invention also provides the cells and cell populations, as well as further products comprising such and uses thereof in bone therapy.
Claims29
1-23. (canceled)
A method for treating a bone-related disorder in a subject in need of such treatment, comprising administering to said subject a therapeutically or prophylactically effective amount of in vitro expanded mesenchymal stem cells (MSCs) originated from human bone marrow, wherein said in vitro expanded MSCs express surface markers comprising CD105 and CD34, and wherein at least 80% of the in vitro expanded MSCs further express surface markers CD90 and CD73.
Dependencies are inferred from the claim text.