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US 2017/0290823 A1Published application
Method of treating parkinson's disease with a diarylmethylpiperazine compounds exhibiting delta opioid receptor agonist activity
AssigneeVersi Group, LLC
InventorsKWEN-JEN CHANG, WILLIAM PENDERGAST, JONATHON D.S. HOLT
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Abstract
Compositions and methods for treatment of Parkinson's disease to reduce the negative side effects of the disease by administering a therapeutically effective diarylmethylpiperazine compound which exhibits delta opioid receptor agonist activity, and optionally, mu receptor antagonist activity.
Claims2
A dose form comprising a transdermal patch affixable to a corporeal locus, and containing a composition for treating Parkinson's disease in a subject experiencing same, comprising at least one compound of the formula selected from the group consisting of:
- and pharmaceutically acceptable esters and salts of the foregoing compounds;
- wherein the amount is sufficient to treat Parkinson's disease wherein the diarylmethylpiperazine compound exhibits delta opioid receptor agonist and mu opioid receptor antagonist activity.
Dependencies are inferred from the claim text.