Pharmaceutical composition for use in increasing the trophism of nasal mucosa
AssigneeBio.Lo.Ga. S.R.L.
InventorsGiorgio Panin, Domenico Testa, Germano Guerra
Life of this patent
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Abstract
Composition for topical application, for use in increasing the trophism of nasal mucosa, comprising an ester of vitamin E with a carboxylic acid of formula R—COOH, in which R is an alkyl radical having 1 to 19 carbon atoms, or an alkenyl or alkynyl radical having 2 to 19 carbon atoms, and an oily vehicle; such composition can be used for the treatment of chronic atrophic rhinitis and for obtaining tissue repair of the nasal mucosa following nasal and sinus surgery.
Claims21
(canceled)
A method of obtaining tissue repair of the nasal mucosa following nasal and sinus surgery, said method comprising administering to a subject in need thereof a therapeutically effective amount of a composition for topical application, said composition comprising an ester of alpha-tocopherol with a carboxylic acid of formula R—COOH, in which R is an alkyl radical having 1 to 19 carbon atoms, or an alkenyl or alkynyl radical having 2 to 19 carbon atoms, and an oily vehicle selected from the group consisting of hydrogenated polyisobutene, hydrogenated polydecene and mixtures of hydrogenated polyisobutene and/or hydrogenated polydecene with hydrogenated polyolefins, Caprylic/Capric Triglyceride, Olus Oil, Adansonia Digitata Oil, Adansonia Digitata Seed Oil, Coco-Caprylate/Caprate, Olive Squalane, Olive Squalene, Sunflower (Helianthus Annus) Seed Oil, Simmondsia Chinensis Oil, Coco-Caprylate, Isononyl Isononanoate, Cyclopentasiloxane, and mixtures thereof.
A method of treating chronic atrophic rhinitis said method comprising administering to a subject in need thereof a therapeutically effective amount of a composition for topical application, said composition comprising an ester of alpha-tocopherol with a carboxylic acid of formula R—COOH, in which R is an alkyl radical having 1 to 19 carbon atoms, or an alkenyl or alkynyl radical having 2 to 19 carbon atoms, and an oily vehicle selected from the group consisting of hydrogenated polyisobutene, hydrogenated polydecene and mixtures of hydrogenated polyisobutene and/or hydrogenated polydecene with hydrogenated polyolefins, Caprylic/Capric Triglyceride, Olus Oil, Adansonia Digitata Oil, Adansonia Digitata Seed Oil, Coco-Caprylate/Caprate, Olive Squalane, Olive Squalene, Sunflower (Helianthus Annus) Seed Oil, Simmondsia Chinensis Oil, Coco-Caprylate, Isononyl Isononanoate, Cyclopentasiloxane, and mixtures thereof.
(canceled)
12-13. (canceled)
Dependencies are inferred from the claim text.